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Fibrous dysplasia of the bone |
This condition affects a number of bones in the body, mostly the long bones. About 20-30% of FD cases are polyostotic. Two thirds of patients exhibit symptoms before the age of 10. Polyostotic FD frequently involves the skull and facial bones, pelvis, spine, and shoulder girdle. The sites of involvement are the femur (91%), tibia (81%), pelvis (78%), ribs, skull and facial bones (50%), upper extremities, lumbar spine, clavicle, and cervical spine, in decreasing order of frequency. There is a thickening of the long bones and the patient usually complains of persistent bone pain. Mild cases are satisfactorily treated with surgery. But in severe cases, radiation therapy has been tried with limited success. The lesions have a high potential to turn malignant.
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